SLC7A11 is an unconventional H+ transporter in lysosomes 2025-04-27
Selective identification of epigenetic regulators at methylated genomic sites by SelectID 2025-04-27
ZBP1 senses splicing aberration through Z-RNA to promote cell death 2025-04-27
A. faecalis induces intestinal T helper 17 cells by promoting E3 ubiquitin ligase Trim21-mediated E3 ubiquitin ligase Fbxw7 degradation 2025-04-11
Proton perception and activation of a proton-sensing GPCR 2025-04-11
Macrophage-targeted Mms6 mRNA-lipid nanoparticles promote locomotor functional recovery after traumatic spinal cord injury in mice 2025-04-07
TCR catch bonds nonlinearly control CD8 cooperation to shape T cell specificity 2025-03-10
Dynamic properties of transcriptional condensates mediate CRISPRa-mediated gene activation 2025-03-05
Establishment of a yeast essential protein conditional degradation library and screening for autophagy-regulating genes 2025-03-05
Structure and function of a broad-range thermal receptor in myriapods 2025-03-05
Mec1-mediated Atg9 phosphorylation regulates the PAS recruitment of Atg9 vesicles upon energy stress 2025-02-24
Rpl12 is a conserved ribophagy receptor 2025-02-24
MFGE8 induces anti-PD-1-therapy resistance by promoting extracellular vesicle sorting of PD-L1 2025-02-24
Dynamics of the mammalian pyruvate dehydrogenase complex revealed by in-situ structural analysis 2025-02-24
Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase 2025-02-24
Deficiency of histamine H2 receptors in parvalbumin-positive neurons leads to hyperactivity, impulsivity, and impaired attention 2025-02-24
Advances and applications in single-cell and spatial genomics 2025-02-24
A bacterial methyltransferase that initiates biotin synthesis, an attractive anti-ESKAPE druggable pathway 2025-02-24
Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A 2025-02-24
A deep learning framework for in silico screening of anticancer drugs at the single-cell level 2025-02-24